CBD For Depression

June 18, 2021

Could Cannabidiol be the answer to your depression? The compound could play a part in relieving you of some of your depression symptoms.

To get a clearer picture we are going to be looking at a study published in a neuropharmacology journal in 2016.

A Study of CBD and Depression

The study suggests that due to the way CBD interacts with the body’s own endocannabinoid system, that it does influence mood.

For those who are unaware, the endocannabinoid system is a biological system found in every mammal that through nerve signalling determines the body’s response to cannabinoids like CBD. One of the areas that it regulates is mood.

It is important to differentiate between THC (the cannabinoid that gets you ‘high’) and CBD – a cannabinoid with no psychoactive properties. CBD has an impact on several receptors in the central nervous system, but its impact on the CB1 and 5-HT1A receptors are thought to result in the biggest impact upon mood.

Previous studies have found CBD to have anxiolytic properties – meaning it reduces anxiety – in rodents and humans. Given the close interconnection between anxiety and depression it is reasonable to assume it could help with the later.

What does the evidence say?

Looking at the behaviour, hyperactivity, and brain tissue in mice, the study concluded that “CBD exerts rapid antidepressant-like effects” and “its efficacy is maintained and improved with the repeated administration”.

So, what does all this mean? And does CBD have any impact over depression? The short answer is yes, it does. Human trails are a bit scarcer than those conducted on rodents, however given the similarity in endocannabinoid system structures in both, it is looking conclusive that CBD does positively impact depression symptoms.

We here at CBD Jenny have first-hand experience of CBD and its ability to help with depression systems, as Jennifer used CBD to aid her in her long journey off anti-depressants (more on that here). And although we are not suggesting CBD is a miracle cure, it is important to acknowledge positive natural alternatives to anti-depressants should someone wish to go down that road.

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